Anticoccidial Activity of Lasalocid (X-537A) in Chicks

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چکیده

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Monomeric forms of the acid ionophore lasalocid A (X-537A) from polar solvents.

X-ray structural analyses have been carried out on the free acid of lasalocid A (X-537A) and on the sodium salt, both crystallized from methanol solution. In each case the structure is monomeric with one molecule of methanol complexing to the free acid and to the salt.

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Hydroxyl deformation frequencies as a probe of hydrogen bonding in lasalocid A (X-537A) and its sodium complex.

The hydroxyl deformation frequencies (900-1 500 cm-l) of lasalocid A, its sodium complex, and their deuterated derivatives were studied with Raman spectroscopy. The secondary and tertiary hydroxyl groups of lasalocid A give rise to spectral lines near 1425, 1303, 1172, and 738 cm-’, typical of hydrogen-bonded hydroxyl groups. In the lasalocid A-sodium complex, these are replaced by peaks at 138...

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Conformation of antibiotic X-537A (lasalocid-A) and its calcium complex in acetonitrile solvent using circular dichroism spectroscopy.

The calcium binding characteristics of antibiotic X-537A (lasalocid-A) in a lipophilic solvent, acetonitrile (CH3CN), have been studied using circular dichroism (CD) spectroscopy. The analysis of the data indicated that in this medium polar solvent, X-537A forms predominantly the charged complexes of stoichiometries 2:1 and 1:1, the relative amounts of the two being dependent on [Ca2+]. The con...

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comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

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ژورنال

عنوان ژورنال: Poultry Science

سال: 1974

ISSN: 0032-5791

DOI: 10.3382/ps.0531448